---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-21-282945"
form_type: "8-K/A"
ticker: "SLDB"
cik: "0001707502"
company_name: "Solid Biosciences Inc."
filed_at: "2021-09-27T23:59:59+00:00"
generated_at: "2026-06-29T01:19:16.271558+00:00"
event_type: "other_material"
sentiment: "neutral"
materiality_score: 0.45
calibrated_materiality_score: 0.45
confidence: "high"
source: SEC EDGAR
---

# Solid Biosciences corrects FVC data error for patient five in IGNITE DMD trial; mean improvement +8.5%

## Summary
- Corrected 1.5-year FVC change for patient five: +22.5% (previously reported incorrectly).
- Mean percent predicted FVC improvement for patients 4-6: +8.5% (range +0.6% to +22.5%).
- Mean difference vs natural history decline of 7.5% was +16.0% over 1.5 years.
- All three patients treated with 2E14 vg/kg SGT-001 show stability or improvement.

## SEC filing metadata
- accession: 0001193125-21-282945
- form_type: 8-K/A
- ticker: SLDB
- cik: 0001707502
- company_name: Solid Biosciences Inc.
- filed_at: 2021-09-27T23:59:59+00:00
- event_type: other_material
- sentiment: neutral
- materiality_score: 0.45
- calibrated_materiality_score: 0.45
- confidence: high
- sec_items: 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1707502/000119312521282945/0001193125-21-282945-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1707502/000119312521282945/d231696d8ka.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-21-282945
- JSON: https://secwatch.observer/filing/0001193125-21-282945.json
- Plain text: https://secwatch.observer/filing/0001193125-21-282945.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.