---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-21-298277"
form_type: "8-K"
ticker: "CRSP"
cik: "0001674416"
company_name: "CRISPR Therapeutics AG"
filed_at: "2021-10-14T23:59:59+00:00"
generated_at: "2026-06-28T20:51:42.653079+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# CRISPR Therapeutics appoints Brendan Smith as CFO; Michael Tomsicek retires

## Summary
- Brendan Smith named SVP & CFO effective Oct 14, 2021; succeeds Michael Tomsicek who retired.
- Smith previously CFO at Translate Bio (acquired by Sanofi for $3.2B) and partner at BCG.
- Smith receives $435K base salary, 40% bonus target, 90K options and 15K RSUs with standard vesting.
- Tomsicek to remain in advisory role through Dec 31, 2021; his departure not due to any accounting disagreement.

## SEC filing metadata
- accession: 0001193125-21-298277
- form_type: 8-K
- ticker: CRSP
- cik: 0001674416
- company_name: CRISPR Therapeutics AG
- filed_at: 2021-10-14T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1674416/000119312521298277/0001193125-21-298277-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1674416/000119312521298277/d212374d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-21-298277
- JSON: https://secwatch.observer/filing/0001193125-21-298277.json
- Plain text: https://secwatch.observer/filing/0001193125-21-298277.txt

## Key facts
- Executive change
  Brendan Smith was appointed as Senior Vice President and Chief Financial Officer at CRISPR Therapeutics AG.
  - Action: appointed
  - Role: Senior Vice President and Chief Financial Officer
  source text: On October 14, 2021, CRISPR Therapeutics AG (the “Company”) announced the hiring and appointment of Brendan Smith as its Senior Vice President and Chief Financial Officer, effective immediately.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1674416/000119312521298277/0001193125-21-298277-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.