---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-22-044916"
form_type: "8-K"
ticker: "RGEN"
cik: "0000730272"
company_name: "REPLIGEN CORP"
filed_at: "2022-02-17T23:59:59+00:00"
generated_at: "2026-06-27T07:11:54.468586+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.85
calibrated_materiality_score: 0.85
confidence: "high"
source: SEC EDGAR
---

# Repligen Q4 revenue $186.5M (+72% YoY); FY 2022 guidance $800-830M (19-24% growth)

## Summary
- Q4 revenue $186.5M (+72% YoY, organic +69%); GAAP EPS $0.50, adjusted EPS $0.81.
- FY 2021 revenue $670.5M (+83% YoY); GAAP EPS $2.24, adjusted EPS $3.06.
- FY 2022 revenue guidance $800-830M (19-24% growth); adjusted EPS guidance $3.21-$3.30.
- Base business contributed 66% of FY revenue; Filtration segment grew ~130% for the year.
- Completed acquisition of BioFlex Solutions; cash $603.8M at year-end.

## SEC filing metadata
- accession: 0001193125-22-044916
- form_type: 8-K
- ticker: RGEN
- cik: 0000730272
- company_name: REPLIGEN CORP
- filed_at: 2022-02-17T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.85
- calibrated_materiality_score: 0.85
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/730272/000119312522044916/0001193125-22-044916-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/730272/000119312522044916/d317056d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-22-044916
- JSON: https://secwatch.observer/filing/0001193125-22-044916.json
- Plain text: https://secwatch.observer/filing/0001193125-22-044916.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.