secwatch.observer — SEC 8-K summary ====================================== Issuer: Quince Therapeutics, Inc. (QNCX) CIK: 0001662774 Form: 8-K Filed at: 2022-05-02T23:59:59+00:00 Accession: 0001193125-22-137040 Event type: leadership Sentiment: negative Materiality: 0.75 Item codes: 2.05, 5.02 LLM model: deepseek-v4-flash:cloud@v2 Cortexyme cuts 36% more staff (67% total); CMO Michael Detke departs May 2 -------------------------------------------------------------------------- - Additional 36% headcount reduction, bringing total to 67% from January 2022 levels; majority by end of May 2022. - Estimated $0.7M in cash expenses for severance and related costs. - CMO Michael Detke to step down effective May 2, 2022; cash severance of $354,750 (9 months base salary). - Additional cash severance and accelerated vesting if change in control within 3 months of departure. - Cost reductions triggered by clinical hold on atuzaginstat (COR388) IND. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1662774/000119312522137040/0001193125-22-137040-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1662774/000119312522137040/d310630d8k.htm HTML page: https://secwatch.observer/filing/0001193125-22-137040 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer