secwatch.observer — SEC 8-K summary ====================================== Issuer: Tyra Biosciences, Inc. (TYRA) CIK: 0001863127 Form: 8-K Filed at: 2022-05-05T23:59:59+00:00 Accession: 0001193125-22-142331 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tyra Biosciences Q1 net loss $14.8M; cash $292.5M; IND filings on track for 2022 -------------------------------------------------------------------------------- - Net loss of $14.8M in Q1 2022 vs $4.2M in Q1 2021, driven by higher R&D and G&A expenses. - R&D expense $9.6M (up from $3.5M); G&A expense $5.2M (up from $0.7M). - Cash and equivalents $292.5M as of March 31, 2022, supporting pipeline into clinical stage. - IND for TYRA-300 (FGFR3 inhibitor) expected mid-2022; TYRA-200 (FGFR2) IND in H2 2022. - Pipeline includes programs in achondroplasia, RET, and FGFR4-driven cancers. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1863127/000119312522142331/0001193125-22-142331-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1863127/000119312522142331/d350831d8k.htm HTML page: https://secwatch.observer/filing/0001193125-22-142331 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer