{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-22-148082","form_type":"8-K","ticker":"SYBX","cik":"0001527599","company_name":"SYNLOGIC, INC.","filed_at":"2022-05-12T23:59:59+00:00","discovered_at":"2026-05-14T18:04:01.066917+00:00","generated_at":"2026-06-25T18:14:30.853376+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Synlogic reports Q1 net loss of $15.7M; cash $120.5M supports runway into 2024","bullets":["Net loss of $15.7M ($0.22/share) vs $15.0M ($0.36/share) in Q1 2021.","Revenue of $0.2M from Roche collaboration; no revenue in Q1 2021.","Cash, cash equivalents and short-term investments $120.5M; expected funding into 2024.","PKU program progressing to Phase 3 readiness; expects Phase 2 data and candidate selection in H2 2022.","Michael Jensen appointed CFO in March 2022."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-22-148082","json":"https://secwatch.observer/filing/0001193125-22-148082.json","markdown":"https://secwatch.observer/filing/0001193125-22-148082.md","text":"https://secwatch.observer/filing/0001193125-22-148082.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1527599/000119312522148082/0001193125-22-148082-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1527599/000119312522148082/d337665d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-25T18:14:30.853376+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}