{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-22-196384","form_type":"8-K","ticker":"CLYM","cik":"0001768446","company_name":"Climb Bio, Inc.","filed_at":"2022-07-18T23:59:59+00:00","discovered_at":"2026-05-14T18:03:56.967819+00:00","generated_at":"2026-06-24T13:33:07.262610+00:00","sec_items":["8.01"],"event_type":"other_material","sentiment":"negative","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Eliem delays ETX-155 Phase 2a MDD trial to Q1 2023 after lower exposure in PSE trial; CMC issue identified","bullets":["Lower-than-expected ETX-155 exposure in Phase 1b photosensitive epilepsy trial attributed to CMC batch inconsistencies.","Phase 1 PK trial in healthy subjects expected Q4 2022 to determine dose for Phase 2a MDD trial.","Phase 2a MDD trial now expected to start Q1 2023 with topline data in mid-2024.","Phase 2a PMD trial postponed to preserve investment flexibility; PSE trial paused pending PK data.","Cash ($149.9M as of March 2022) expected to fund operations and pipeline catalysts through mid-2024."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-22-196384","json":"https://secwatch.observer/filing/0001193125-22-196384.json","markdown":"https://secwatch.observer/filing/0001193125-22-196384.md","text":"https://secwatch.observer/filing/0001193125-22-196384.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1768446/000119312522196384/0001193125-22-196384-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1768446/000119312522196384/d385261d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-24T13:33:07.262610+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}