other material
confidence high
sentiment neutral
materiality 0.30
Vaccinex presents pepinemab AD/HD data at AAIC 2022; SIGNAL-AD first patient completed with no safety concerns
VACCINEX, INC.
- Presented poster at AAIC 2022 on pepinemab (SEMA4D antibody) for Alzheimer's and Huntington's disease.
- Phase 2 HD study showed pepinemab restored learning and increased brain metabolic activity (FDG-PET).
- Ongoing Phase 1/2a SIGNAL-AD study: first patient completed with no safety concerns as of Q2 2022.
- Pepinemab targets glial activation to reduce neuroinflammation; funded by Alzheimer's Association and ADDF.