---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-22-274508"
form_type: "8-K"
ticker: "RGEN"
cik: "0000730272"
company_name: "REPLIGEN CORP"
filed_at: "2022-11-01T23:59:59+00:00"
generated_at: "2026-06-22T19:56:33.939081+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Repligen Q3 revenue $200.7M (+13% YoY); raises FY revenue guidance to $795-$805M

## Summary
- Revenue $200.7M, +13% reported, +19% constant currency, +16% organic; base business up 29% YoY.
- GAAP EPS $0.71; adjusted EPS $0.77 (vs $0.78 Q3 2021); GAAP gross margin 56.9%.
- FY 2022 revenue guidance raised to $795-$805M (from $790-$810M); base business growth raised to 33%-34%.
- Adjusted EPS guidance narrowed to $3.15-$3.20 from $3.13-$3.20; operating income guidance lowered to $231-$235M.
- Signed 15-year real-time process monitoring deal with DRS Daylight Solutions; extended Purolite affinity ligand agreement to 2032.

## SEC filing metadata
- accession: 0001193125-22-274508
- form_type: 8-K
- ticker: RGEN
- cik: 0000730272
- company_name: REPLIGEN CORP
- filed_at: 2022-11-01T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/730272/000119312522274508/0001193125-22-274508-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/730272/000119312522274508/d394510d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-22-274508
- JSON: https://secwatch.observer/filing/0001193125-22-274508.json
- Plain text: https://secwatch.observer/filing/0001193125-22-274508.txt

## Key facts
- Earnings Releases
  REPLIGEN CORP reported the year 2022 results: revenue $795-$805 million.
  - Period: the year 2022
  - Revenue: $795-$805 million
  - Result: guidance update
  source text: YEAR 2022 GUIDANCE: • Total reported revenue is expected to be in the range of $795-$805 million, compared to our previous guidance of $790-$810 million.
  evidence_url: https://www.sec.gov/Archives/edgar/data/730272/000119312522274508/0001193125-22-274508-index.htm
- Earnings Releases
  REPLIGEN CORP reported the third quarter ended September 30, 2022 results: revenue $200.7 million, net income $40.4 million, EPS $0.71 on a fully diluted basis.
  - Period: the third quarter ended September 30, 2022
  - Revenue: $200.7 million
  - Net income: $40.4 million
  - EPS: $0.71 on a fully diluted basis
  - Result: reported results
  source text: Total revenue as reported for the third quarter of 2022 increased to $200.7 million compared to $178.2 million for the third quarter of 2021, a year-over-year gain of 13%, or 19% at constant currency, and organic growth of 16%.
  evidence_url: https://www.sec.gov/Archives/edgar/data/730272/000119312522274508/0001193125-22-274508-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.