{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-22-275812","form_type":"8-K","ticker":"AMLX","cik":"0001658551","company_name":"Amylyx Pharmaceuticals, Inc.","filed_at":"2022-11-02T23:59:59+00:00","discovered_at":"2026-05-14T18:03:51.605113+00:00","generated_at":"2026-06-22T14:23:28.952051+00:00","sec_items":["5.02"],"event_type":"leadership","sentiment":"neutral","materiality_score":0.25,"calibrated_materiality_score":0.25,"confidence":"high","headline":"Director Isaac Cheng resigns from Amylyx board effective Nov 1, 2022","bullets":["Isaac Cheng, MD, resigned from the board of directors on November 1, 2022.","Resignation is not due to any disagreement with the company on operations, policies, or accounting.","Board size reduced by one; no replacement named in the filing.","Company thanked Dr. Cheng for his service and contributions."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-22-275812","json":"https://secwatch.observer/filing/0001193125-22-275812.json","markdown":"https://secwatch.observer/filing/0001193125-22-275812.md","text":"https://secwatch.observer/filing/0001193125-22-275812.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1658551/000119312522275812/0001193125-22-275812-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1658551/000119312522275812/d374833d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-22T14:23:28.952051+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"c218aa04ef","claim":"Isaac Cheng resigned as Member of the Board of Directors at Amylyx Pharmaceuticals, Inc..","evidence_excerpt":"On November 1, 2022, Isaac Cheng, MD, a member of the board of directors of Amylyx Pharmaceuticals, Inc. (the “Company”), submitted his resignation from the board of directors, effective as of close of business on November 1, 2022.","evidence_source":"SEC 8-K Item 5.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1658551/000119312522275812/0001193125-22-275812-index.htm","confidence":0.95,"family_label":"Executive change","details":[{"label":"Action","value":"resigned"},{"label":"Role","value":"Member of the Board of Directors"}],"fact_type":"executive_change"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}