earnings
confidence high
sentiment positive
materiality 0.75
Alaunos reports Q3 net loss $8.9M; first objective response in TCR-T Library trial
Alaunos Therapeutics, Inc.
2022-Q3 EPS reported
-$0.13
revenue$2,911,000
- Q3 2022 net loss $8.9M ($0.04/sh) vs $22.7M ($0.11/sh) in Q3 2021; revenue $2.9M from darinaparsin milestone.
- First patient with NSCLC achieved >50% tumor regression at 12 weeks with Sleeping Beauty TCR-T cells targeting KRAS G12D.
- TCR-T cell persistence observed: ~30% of blood T-cells at 24 weeks in patient 1; manageable safety, no ICANS.
- Manufacturing capacity doubled to produce two products simultaneously; IND amendment in 4Q22 to add two TCRs and switch to cryopreserved process (26 days vs 30).
- Cash $37.8M plus restricted cash $13.9M; operating cash burn $6.1M in Q3 2022, down 36% YoY.