other material
confidence high
sentiment positive
materiality 0.75
Synlogic reports SYNB8802 Phase 1b proof of concept: -38% urinary oxalate reduction in enteric hyperoxaluria
SYNLOGIC, INC.
- SYNB8802 reduced urinary oxalate by 38% vs placebo at 3x10^11 TID dose in Roux-en-Y gastric bypass patients.
- No serious adverse events; GI AEs mild and similar in frequency between active and placebo groups.
- Third positive clinical readout for Synlogic in 2022, following SYNB1934 for PKU and SYNB1353 for homocystinuria.
- Company to host webcast today at 8:30 AM ET with Dr. Kyle Wood of UAB.