---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-002932"
form_type: "8-K"
ticker: "ANNX"
cik: "0001528115"
company_name: "Annexon, Inc."
filed_at: "2023-01-06T23:59:59+00:00"
generated_at: "2026-06-20T18:45:53.828658+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Annexon appoints Dr. Rick Artis as Chief Scientific Officer, succeeding Dr. Larry Mattheakis

## Summary
- Dean 'Rick' Artis, Ph.D., appointed CSO effective January 6, 2023, succeeding Larry C. Mattheakis who is departing.
- Artis previously served as SVP of Chemistry at Annexon and discovered small molecule ANX1502.
- Artis most recently was CSO at Octant Bio and has discovery-to-clinic experience across multiple therapeutic areas.
- He will lead all research efforts with focus on expanding small molecule pipeline and advancing complement portfolio.

## SEC filing metadata
- accession: 0001193125-23-002932
- form_type: 8-K
- ticker: ANNX
- cik: 0001528115
- company_name: Annexon, Inc.
- filed_at: 2023-01-06T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1528115/000119312523002932/0001193125-23-002932-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1528115/000119312523002932/d426219d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-002932
- JSON: https://secwatch.observer/filing/0001193125-23-002932.json
- Plain text: https://secwatch.observer/filing/0001193125-23-002932.txt

## Key facts
- Executive change
  Larry C. Mattheakis departed as Chief Scientific Officer at Annexon, Inc..
  - Action: departed
  - Role: Chief Scientific Officer
  source text: Dr. Artis is succeeding Larry C. Mattheakis, Ph.D., who is departing from the Company and is no longer serving as Chief Scientific Officer effective as of January 6, 2023.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1528115/000119312523002932/0001193125-23-002932-index.htm
- Executive change
  Dean Richard Artis was appointed as Chief Scientific Officer at Annexon, Inc..
  - Action: appointed
  - Role: Chief Scientific Officer
  source text: the appointment of Dean Richard Artis, Ph.D. as Chief Scientific Officer of the Company.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1528115/000119312523002932/0001193125-23-002932-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.