{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-23-002979","form_type":"8-K","ticker":"SYRE","cik":"0001636282","company_name":"Spyre Therapeutics, Inc.","filed_at":"2023-01-06T23:59:59+00:00","discovered_at":"2026-05-14T18:03:45.946373+00:00","generated_at":"2026-06-20T18:49:51.734003+00:00","sec_items":["5.02"],"event_type":"leadership","sentiment":"neutral","materiality_score":0.55,"calibrated_materiality_score":0.55,"confidence":"high","headline":"Aeglea BioTherapeutics COO Leslie Sloan departs Jan 5, 2023; receives severance package","bullets":["COO Leslie Sloan departed Jan 5, 2023; departure not tied to legal or compliance matters.","Severance includes $435,000 salary continuation (12 months), $174,000 lump-sum bonus, and 12 months COBRA coverage.","Unvested stock options accelerate vesting for an additional 12 months beyond separation date.","No successor COO has been announced."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-23-002979","json":"https://secwatch.observer/filing/0001193125-23-002979.json","markdown":"https://secwatch.observer/filing/0001193125-23-002979.md","text":"https://secwatch.observer/filing/0001193125-23-002979.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1636282/000119312523002979/0001193125-23-002979-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1636282/000119312523002979/d380211d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-20T18:49:51.734003+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"412d2885ec","claim":"Leslie Sloan departed as Chief Operating Officer at Spyre Therapeutics, Inc..","evidence_excerpt":"Effective January 5, 2023 (the “Separation Date”), Leslie Sloan will no longer serve as Chief Operating Officer of Aeglea BioTherapeutics, Inc. (the “Company”).","evidence_source":"SEC 8-K Item 5.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1636282/000119312523002979/0001193125-23-002979-index.htm","confidence":0.95,"family_label":"Executive change","details":[{"label":"Action","value":"will no longer serve as"},{"label":"Role","value":"Chief Operating Officer"}],"fact_type":"executive_change"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}