---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-021612"
form_type: "8-K"
ticker: "SPRO"
cik: "0001701108"
company_name: "Spero Therapeutics, Inc."
filed_at: "2023-02-01T23:59:59+00:00"
generated_at: "2026-06-20T03:56:02.689118+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.4
calibrated_materiality_score: 0.4
confidence: "high"
source: SEC EDGAR
---

# Spero Therapeutics names Timothy Keutzer Chief Operating Officer effective Feb 1, 2023

## Summary
- Timothy Keutzer, previously Chief Development Officer, appointed COO effective February 1, 2023.
- Base salary set at $459,000; annual cash bonus target of up to 40% of base salary.
- Grant of 4-year vesting RSUs worth $500,000 on effective date.
- Severance: 9 months salary without Cause/Good Reason; on change of control, 12 months salary plus equity acceleration.

## SEC filing metadata
- accession: 0001193125-23-021612
- form_type: 8-K
- ticker: SPRO
- cik: 0001701108
- company_name: Spero Therapeutics, Inc.
- filed_at: 2023-02-01T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.4
- calibrated_materiality_score: 0.4
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1701108/000119312523021612/0001193125-23-021612-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1701108/000119312523021612/d455024d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-021612
- JSON: https://secwatch.observer/filing/0001193125-23-021612.json
- Plain text: https://secwatch.observer/filing/0001193125-23-021612.txt

## Key facts
- Executive change
  Timothy Keutzer was appointed as Chief Operating Officer at Spero Therapeutics, Inc..
  - Action: appointed
  - Role: Chief Operating Officer
  source text: On January 30, 2023, the Board of Directors (the “Board”) of Spero Therapeutics, Inc. (the “Company”) appointed Timothy Keutzer as the Company’s Chief Operating Officer, effective as of February 1, 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1701108/000119312523021612/0001193125-23-021612-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.