other material
confidence high
sentiment positive
materiality 0.85
Phase 2 interim data: 100% tumor control, 88% vision preservation with bel-sar in early choroidal melanoma
Aura Biosciences, Inc.
- 100% tumor control (8/8) and 88% visual acuity preservation in patients receiving three cycles of bel-sar.
- Statistically significant reduction in tumor growth rate: -0.289 mm/yr (p<0.0001) vs. each patient's documented rate.
- No treatment-related SAEs; only mild anterior inflammation (Grade 1) in 20% of patients.
- Company plans to initiate global Phase 3 trial enrollment this year based on these data.
- Data presented at Macula Society 46th Annual Meeting with average 9 months follow-up.