{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-23-045671","form_type":"8-K","ticker":"MDGL","cik":"0001157601","company_name":"MADRIGAL PHARMACEUTICALS, INC.","filed_at":"2023-02-23T23:59:59+00:00","discovered_at":"2026-05-14T18:03:43.988573+00:00","generated_at":"2026-06-19T01:33:15.886555+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"Madrigal reports Q4 2022 cash $358.8M; positive Phase 3 NASH results support H1 2023 NDA filing","bullets":["Cash, cash equivalents and marketable securities $358.8M at Dec 31, 2022, up from $270.3M at Dec 31, 2021.","Operating expenses $85.3M (Q4) and $293.6M (FY2022), vs $64.6M and $242.5M in prior year periods.","R&D expenses $70.7M (Q4) and $245.4M (FY2022), increases due to Phase 3 trials and headcount.","Positive Phase 3 MAESTRO-NASH results achieved both primary endpoints; NDA filing for resmetirom planned H1 2023.","Secured $250M term loan facility with Hercules Capital and $300M+ in financing events in 2022."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-23-045671","json":"https://secwatch.observer/filing/0001193125-23-045671.json","markdown":"https://secwatch.observer/filing/0001193125-23-045671.md","text":"https://secwatch.observer/filing/0001193125-23-045671.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1157601/000119312523045671/0001193125-23-045671-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1157601/000119312523045671/d449135d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-19T01:33:15.886555+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}