other material
confidence high
sentiment positive
materiality 0.55
IN8bio announces positive preclinical data for nsCAR platform and launches INB-330 program at AACR 2023
IN8BIO, INC.
- nsCAR platform showed ability to target cancer cells while sparing healthy tissue; ns19CAR killed 80% of leukemia cells vs 5% of healthy B cells.
- Launched INB-330 program targeting CD33 in AML; ns33CAR demonstrated anti-leukemic activity against AML, B-ALL, and CML cell lines.
- Data presented at AACR Annual Meeting 2023; management highlights potential to address previously 'undruggable' targets.
- Company seeks potential partners for further evaluation of nsCAR platform with additional targets.