---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-131300"
form_type: "8-K"
ticker: "RGEN"
cik: "0000730272"
company_name: "REPLIGEN CORP"
filed_at: "2023-05-02T23:59:59+00:00"
generated_at: "2026-06-16T04:09:51.622613+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Repligen Q1 revenue $182.7M, down 12% YoY; cuts full-year guidance on macro headwinds

## Summary
- GAAP EPS $0.51 (down 37% YoY); adjusted EPS $0.64 (down 30% YoY); gross margin 55.2% (down 520 bps).
- Total revenue guidance cut to $720-760M (prev $760-800M); base business growth lowered to 4-8% (prev 11-15%).
- Completed acquisition of single-use bag maker FlexBiosys in April; adds to Fluid Management portfolio.
- Sees softness in AsiaPac (especially China) and slower order recovery; COVID-related revenue expected $30-40M.

## SEC filing metadata
- accession: 0001193125-23-131300
- form_type: 8-K
- ticker: RGEN
- cik: 0000730272
- company_name: REPLIGEN CORP
- filed_at: 2023-05-02T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/730272/000119312523131300/0001193125-23-131300-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/730272/000119312523131300/d390182d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-131300
- JSON: https://secwatch.observer/filing/0001193125-23-131300.json
- Plain text: https://secwatch.observer/filing/0001193125-23-131300.txt

## Key facts
- Earnings Releases
  REPLIGEN CORP reported first quarter ended March 31, 2023 results: revenue $182.7 million, net income $28.8 million, EPS $0.51. Guidance lowered.
  - Period: first quarter ended March 31, 2023
  - Revenue: $182.7 million
  - Net income: $28.8 million
  - EPS: $0.51
  - Guidance: lowered
  - Result: reported results
  source text: REVENUE • Total revenue for the first quarter of 2023 was $182.7 million compared to $206.4 million for the first quarter of 2022, a year-over-year decrease of 12% as reported, and down 9% at constant currency. GROSS PROFIT and GROSS MARGIN • Gross profit (GAAP) for the first quarter of 2023 was $100.8 million compared to $124.0 million for the first quarter of 2022. Adjusted gross profit (non-GAAP) for the first quarter of 2023 was $100.8 million, a decrease of 19% compared to $124.6 million for the first quarter of 2022. • Gross margin (GAAP) for the first quarter of 2023 was 55.2%, compared to 60.1% for the first quarter of 2022. Adjusted gross margin (non-GAAP) for the first quarter was 55.2%, compared to 60.4% in the 2022 period, a year-over-year decrease of approximately 520 basis points. INCOME FROM OPERATIONS • Income from operations (GAAP) for the first quarter of 2023 was $31.3 million, compared to $60.0 million for the first quarter of 2022. Our GAAP income from operations f
  evidence_url: https://www.sec.gov/Archives/edgar/data/730272/000119312523131300/0001193125-23-131300-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.