secwatch.observer — SEC 8-K summary ====================================== Issuer: Spero Therapeutics, Inc. (SPRO) CIK: 0001701108 Form: 8-K Filed at: 2023-05-11T23:59:59+00:00 Accession: 0001193125-23-142023 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Spero Therapeutics reports Q1 2023 net loss of $13.3M; provides pipeline updates for SPR720, tebipenem HBr, and SPR206 -------------------------------------------------------------------------------- - Net loss of $13.3M ($0.25 per share) in Q1 2023, compared to net loss of $32.8M ($1.01 per share) in Q1 2022. - Cash and cash equivalents of $96.3M as of March 31, 2023; company expects sufficient funding beyond 2024. - SPR720 Phase 2 trial in NTM-PD on track for top line data readout in first half of 2024. - Tebipenem HBr: SPA agreement update expected mid-2023; Phase 3 cUTI trial initiation expected in 2H 2023. - SPR206: IND submission for Phase 2 trial in hospital-acquired/ventilator-associated bacterial pneumonia expected Q4 2023. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1701108/000119312523142023/0001193125-23-142023-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1701108/000119312523142023/d438048d8k.htm HTML page: https://secwatch.observer/filing/0001193125-23-142023 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer