other material
confidence high
sentiment positive
materiality 0.65
IN8bio Phase 1 INB-200 data shows 100% of GBM patients exceed historical median PFS
IN8BIO, INC.
- 100% (8/8) patients exceeded historical median PFS of 4-7 months; two patients from three-dose cohort remain progression-free at 23.5 and 19.4 months.
- No treatment-related SAEs, DLTs, CRS, or ICANS reported; common TEAEs mild and linked to temozolomide.
- Cohort 1 PFS ranged 7.4–11.9 months; Cohort 3 first patient had 7.1 months PFS with no brain progression.
- Company on track to complete Phase 1 enrollment in 2023; further updates expected later this year.