---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-209172"
form_type: "8-K"
ticker: "QNCX"
cik: "0001662774"
company_name: "Quince Therapeutics, Inc."
filed_at: "2023-08-10T23:59:59+00:00"
generated_at: "2026-06-11T17:58:11.494543+00:00"
event_type: "leadership"
sentiment: "negative"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Quince Therapeutics CMO Karen Smith to depart effective Sept 1, 2023

## Summary
- Chief Medical Officer Karen Smith, M.D., Ph.D. will depart on September 1, 2023.
- Separation agreement includes 12 months base salary severance plus prorated 2023 bonus and health benefits lump sum.
- Outstanding equity awards subject to 50% accelerated vesting; additional benefits if change in control occurs within 3 months after departure.
- Dr. Smith will continue as employee until the departure date under transition and separation agreement.

## SEC filing metadata
- accession: 0001193125-23-209172
- form_type: 8-K
- ticker: QNCX
- cik: 0001662774
- company_name: Quince Therapeutics, Inc.
- filed_at: 2023-08-10T23:59:59+00:00
- event_type: leadership
- sentiment: negative
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1662774/000119312523209172/0001193125-23-209172-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1662774/000119312523209172/d538151d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-209172
- JSON: https://secwatch.observer/filing/0001193125-23-209172.json
- Plain text: https://secwatch.observer/filing/0001193125-23-209172.txt

## Key facts
- Executive change
  Karen Smith departed as Chief Medical Officer at Quince Therapeutics, Inc..
  - Action: departure
  - Role: Chief Medical Officer
  source text: On July 24, 2023, Quince Therapeutics, Inc. (the “Company”) announced the departure of Karen Smith, M.D., Ph.D., the Company’s Chief Medical Officer, effective as of September 1, 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1662774/000119312523209172/0001193125-23-209172-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.