---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-209727"
form_type: "8-K"
ticker: "SYRE"
cik: "0001636282"
company_name: "Spyre Therapeutics, Inc."
filed_at: "2023-08-11T23:59:59+00:00"
generated_at: "2026-06-11T14:39:02.302377+00:00"
event_type: "other_material"
sentiment: "negative"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Aeglea BioTherapeutics terminates Austin office lease, pays $2M termination fee

## Summary
- Terminated lease for Suites 100, 110, and 150 at 805 Las Cimas Parkway, Austin, TX effective Aug 8, 2023.
- Lease originally dated April 30, 2019, amended Oct 2019 and Jan 2020; terminated via agreement with Landlord Las Cimas Owner LP.
- Company paid a termination fee of $2 million as consideration for release from all future obligations under the lease.
- No further obligations to Landlord arise or accrue from and after the Termination Date.

## SEC filing metadata
- accession: 0001193125-23-209727
- form_type: 8-K
- ticker: SYRE
- cik: 0001636282
- company_name: Spyre Therapeutics, Inc.
- filed_at: 2023-08-11T23:59:59+00:00
- event_type: other_material
- sentiment: negative
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 1.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1636282/000119312523209727/0001193125-23-209727-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1636282/000119312523209727/d530241d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-209727
- JSON: https://secwatch.observer/filing/0001193125-23-209727.json
- Plain text: https://secwatch.observer/filing/0001193125-23-209727.txt

## Key facts
- Material Agreements
  Spyre Therapeutics, Inc. terminated Lease Agreement dated April 30, 2019, as amended with Las Cimas Owner LP valued at Termination fee of $2,000,000 (effective 2023-08-08).
  - Action: termination
  - Agreement: lease
  - Counterparty: Las Cimas Owner LP
  - Value: Termination fee of $2,000,000
  - Effective: 2023-08-08
  source text: On August 7, 2023, Aeglea BioTherapeutics, Inc. (the “Company”) entered into a lease termination agreement (the “Termination Agreement”) with Las Cimas Owner LP (the “Landlord”) pursuant to which the parties agreed to terminate, as of August 8, 2023 (the “Termination Date”), that certain Lease Agreement dated as of April 30, 2019, as amended on October 2, 2019 and January 14, 2020 (the “Lease”), by and between the Landlord and the Company, pursuant to which the Company leased Suites 100, 110 and 150 located in the office building commonly known as 805 Las Cimas Parkway, Austin, Texas 78746 (the “Premises”).
  evidence_url: https://www.sec.gov/Archives/edgar/data/1636282/000119312523209727/0001193125-23-209727-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.