---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-23-269388"
form_type: "8-K"
ticker: "CDXS"
cik: "0001200375"
company_name: "CODEXIS, INC."
filed_at: "2023-11-02T23:59:59+00:00"
generated_at: "2026-06-08T23:27:11.447631+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Codexis Q3 net loss widens to $34.9M; revenue ex-PAXLOVID falls 57% to $9.3M

## Summary
- Net loss of $34.9M ($0.50/share) vs $10.0M loss ($0.15) in Q3 2022; adjusted loss $17.9M ($0.26) excludes restructuring/impairments.
- Total revenue $9.3M, down 73% YoY including PAXLOVID; ex-PAXLOVID revenue down 57% to $9.3M.
- Cash $74.6M; expects runway to positive cash flow around end of 2026.
- Reaffirms FY2023 guidance: product revenue $30-35M (ex-PAXLOVID), R&D revenue $21-24M, gross margin 55-65%.
- ECO Synthesis platform on track for gram-scale synthesis by year-end; dsRNA ligase wide availability in H2 2024.

## SEC filing metadata
- accession: 0001193125-23-269388
- form_type: 8-K
- ticker: CDXS
- cik: 0001200375
- company_name: CODEXIS, INC.
- filed_at: 2023-11-02T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1200375/000119312523269388/0001193125-23-269388-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1200375/000119312523269388/d581655d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-23-269388
- JSON: https://secwatch.observer/filing/0001193125-23-269388.json
- Plain text: https://secwatch.observer/filing/0001193125-23-269388.txt

## Key facts
- Earnings Releases
  CODEXIS, INC. reported financial results for for the third quarter ended September 30, 2023.
  - Period: for the third quarter ended September 30, 2023
  - Result: reported results
  source text: On November 2, 2023, Codexis, Inc. announced its financial results for the quarter ended September 30, 2023.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1200375/000119312523269388/0001193125-23-269388-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.