secwatch.observer — SEC 8-K summary ====================================== Issuer: Wave Life Sciences Ltd. (WVE) CIK: 0001631574 Form: 8-K Filed at: 2023-11-09T23:59:59+00:00 Accession: 0001193125-23-274068 Event type: earnings Sentiment: positive Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Wave Life Sciences Q3 net income $7.3M; initiates first RNA editing clinical program, WVE-006 -------------------------------------------------------------------------------- - Net income of $7.3M vs net loss of $39.0M YoY; revenue increase driven by $48.9M in collaboration milestones. - Cash $139.9M as of Sep 30, plus $7M milestone received in 4Q; runway into 2025. - Initiated RestorAATion clinical program for WVE-006 (RNA editing for AATD); dosing in 4Q 2023, proof-of-mechanism data in 2024. - Enrolled 30mg multi-dose cohort of SELECT-HD for WVE-003; data in 2Q 2024 to enable Takeda opt-in. - Preclinical INHBE siRNA data for obesity; clinical candidate selection in 4Q 2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1631574/000119312523274068/0001193125-23-274068-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1631574/000119312523274068/d243880d8k.htm HTML page: https://secwatch.observer/filing/0001193125-23-274068 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer