---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-24-004882"
form_type: "8-K"
ticker: "CDXS"
cik: "0001200375"
company_name: "CODEXIS, INC."
filed_at: "2024-01-09T23:59:59+00:00"
generated_at: "2026-06-07T01:18:46.788428+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.55
calibrated_materiality_score: 0.55
confidence: "high"
source: SEC EDGAR
---

# Codexis raises 2023 R&D revenue guidance to $25-27M, updates cash and margin outlook

## Summary
- Unaudited pro forma cash ~$70M as of Dec 31, 2023; includes $5M upfront from Nestlé for CDX-7108 assignment.
- 2023 product revenue expected at upper end of $30M-$35M range (excl. PAXLOVID enzyme sales).
- R&D revenue guidance raised to $25M-$27M from $21M-$24M, reflecting $5M Q1 payment from Nestlé.
- Gross margin on product revenue guidance raised to 60%-65% from 55%-65% (excl. PAXLOVID).
- Cash expected to fund operations to positive cash flow around end of 2026.

## SEC filing metadata
- accession: 0001193125-24-004882
- form_type: 8-K
- ticker: CDXS
- cik: 0001200375
- company_name: CODEXIS, INC.
- filed_at: 2024-01-09T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.55
- calibrated_materiality_score: 0.55
- confidence: high
- sec_items: 2.02, 7.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1200375/000119312524004882/0001193125-24-004882-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1200375/000119312524004882/d710983d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-24-004882
- JSON: https://secwatch.observer/filing/0001193125-24-004882.json
- Plain text: https://secwatch.observer/filing/0001193125-24-004882.txt

## Key facts
- Earnings Releases
  CODEXIS, INC. updated its full year 2023 guidance (reaffirmed).
  - Period: full year 2023
  - Guidance: reaffirmed
  - Result: preliminary results
  source text: On January 9, 2024, Codexis, Inc. (the “Company”) reported unaudited pro forma cash and cash equivalents of approximately $70 million as of December 31, 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1200375/000119312524004882/0001193125-24-004882-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.