---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-24-042887"
form_type: "8-K"
ticker: "SYBX"
cik: "0001527599"
company_name: "SYNLOGIC, INC."
filed_at: "2024-02-22T23:59:59+00:00"
generated_at: "2026-06-05T19:12:33.862282+00:00"
event_type: "leadership"
sentiment: "negative"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Synlogic CEO Aoife Brennan to depart March 9; COO Antoine Awad to leave May 30

## Summary
- CEO Dr. Aoife Brennan's employment ends March 9, 2024; receives $628,305 severance (12 months base).
- COO Antoine Awad's employment ends May 30, 2024; receives $218,856 severance (6 months base).
- Both executives eligible for pro-rated 2024 bonuses: CEO $65,327, COO $87,302, at Company discretion.
- Health insurance coverage extended: CEO up to 12 months, COO up to 6 months post-departure.
- No replacement named for either role; transitions in progress.

## SEC filing metadata
- accession: 0001193125-24-042887
- form_type: 8-K
- ticker: SYBX
- cik: 0001527599
- company_name: SYNLOGIC, INC.
- filed_at: 2024-02-22T23:59:59+00:00
- event_type: leadership
- sentiment: negative
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1527599/000119312524042887/0001193125-24-042887-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1527599/000119312524042887/d793484d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-24-042887
- JSON: https://secwatch.observer/filing/0001193125-24-042887.json
- Plain text: https://secwatch.observer/filing/0001193125-24-042887.txt

## Key facts
- Executive change
  Aoife Brennan was terminated as President and Chief Executive Officer at SYNLOGIC, INC..
  - Action: terminated
  - Role: President and Chief Executive Officer
  source text: Synlogic, Inc. (the “ Company ”) and Aoife Brennan, M.B., Ch.B., President and Chief Executive Officer, agreed that Dr. Brennan’s employment with the Company will terminate effective March 9, 2024
  evidence_url: https://www.sec.gov/Archives/edgar/data/1527599/000119312524042887/0001193125-24-042887-index.htm
- Executive change
  Antoine Awad departed as Chief Operating Officer at SYNLOGIC, INC..
  - Action: will end
  - Role: Chief Operating Officer
  source text: Mr. Awad’s employment with the Company will end on May 30, 2024
  evidence_url: https://www.sec.gov/Archives/edgar/data/1527599/000119312524042887/0001193125-24-042887-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.