secwatch.observer — SEC 8-K summary ====================================== Issuer: ACADIA PHARMACEUTICALS INC (ACAD) CIK: 0001070494 Form: 8-K Filed at: 2024-03-11T23:59:59+00:00 Accession: 0001193125-24-064791 Event type: other_material Sentiment: negative Materiality: 0.85 Item codes: 8.01 LLM model: deepseek-v4-flash:cloud@v2 ACAD's Phase 3 ADVANCE-2 trial of pimavanserin misses primary endpoint in negative symptoms of schizophrenia -------------------------------------------------------------------------------- - Pimavanserin failed Phase 3 ADVANCE-2 trial for negative symptoms of schizophrenia; primary endpoint not met. - Safety and tolerability consistent with prior trials, showing low adverse event rate. - No financial or regulatory guidance provided in this 8-K; further analysis may follow. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1070494/000119312524064791/0001193125-24-064791-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1070494/000119312524064791/d786050d8k.htm HTML page: https://secwatch.observer/filing/0001193125-24-064791 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer