M&A
confidence high
sentiment positive
materiality 1.00
Vertex to acquire Alpine for $65/share (~$4.9B); deal expected to close Q2 2024
ALPINE IMMUNE SCIENCES, INC.
- Total equity value ~$4.9B; Vertex will pay $65 per share in cash.
- Alpine’s lead drug povetacicept (dual BAFF/APRIL antagonist) showed best-in-class potential in IgA nephropathy; Phase 3 planned H2 2024.
- Stockholders owning ~25.5% of shares have agreed to tender; termination fee of $173M payable by Alpine under certain conditions.
- Transaction unanimously approved by both boards; expected to close in Q2 2024, subject to HSR and tender of majority of shares.
- Alpine’s pipeline includes studies in membranous nephropathy, lupus nephritis, and autoimmune cytopenias.