earnings
confidence high
sentiment negative
materiality 0.70
Disc Medicine Q1 net loss $26.9M; bitopertin AURORA trial misses primary endpoint, but shows secondary benefits
Disc Medicine, Inc.
2024-Q1 EPS reported
-$1.09
- Cash and cash equivalents $342.6M at March 31, 2024; provides runway well into 2026.
- Net loss $26.9M in Q1 2024 vs. $22.8M in Q1 2023; R&D expense rose to $23.7M from $20.2M.
- Bitopertin AURORA phase 2 in EPP: significant PPIX reduction; missed primary endpoint (light tolerance) due to placebo benefit; 60mg dose showed significant reduction in phototoxic pain reactions.
- Received FDA Rare Pediatric Disease Designation for bitopertin in EPP in May 2024.
- On track to present additional AURORA/BEACON data, initial DISC-3405 SAD data, and updated DISC-0974 MF data in Q2 2024.