other material
confidence high
sentiment positive
materiality 0.65
J&J Phase 3 seltorexant meets all endpoints; Royalty Pharma holds mid-single-digit royalty
Royalty Pharma plc
- J&J's Phase 3 MDD3001 trial of seltorexant met all primary and secondary endpoints in MDD with insomnia.
- Seltorexant is a first-in-class orexin-2 receptor antagonist; no approved therapies exist for MDD with insomnia.
- Royalty Pharma is entitled to a mid-single-digit royalty on worldwide net sales of seltorexant.
- J&J previously estimated non-risk adjusted peak sales potential of $1B–$5B for seltorexant.