other material
confidence high
sentiment positive
materiality 0.75
Benitec reports durable swallowing improvements at 180 days for first BB-301 subject in Phase 1b/2a
Benitec Biopharma Inc.
- Post-dose Total Pharyngeal Residue meaningfully reduced at 180 days vs pre-dose average for Subject 1.
- For 3 of 4 food types, TPR at 180 days lower than any point in 9-month natural history study; fourth similar to lowest.
- SSQ Total Score at 180 days lower than any point in 9-month pre-dose period, indicating improved swallowing.
- No SAEs observed; transient Grade 2 GERD previously reported.
- Second subject dosed Feb 2024; third expected Q3 2024; additional interim data in Q1 2025.