{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-24-196489","form_type":"8-K","ticker":"WVE","cik":"0001631574","company_name":"Wave Life Sciences Ltd.","filed_at":"2024-08-08T23:59:59+00:00","discovered_at":"2026-05-14T18:03:13.874637+00:00","generated_at":"2026-05-31T10:58:13.848546+00:00","sec_items":["2.02","7.01","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Wave Life Sciences Q2 net loss $32.9M; positive HD data with up to 46% mHTT reduction; cash $154M into Q4 2025","bullets":["Q2 net loss $32.9M vs $21.1M YoY; revenue $19.7M vs $22.1M; cash $154M, sufficient into Q4 2025.","SELECT-HD: WVE-003 reduced mutant HTT up to 46%, statistically significant; slowing caudate atrophy; Takeda opt-in submitted.","DMD: FORWARD-53 dystrophin data expected 3Q2024; WVE-N531 previously showed 53% exon skipping.","AATD: RestorAATion-2 dosing initiated; proof-of-mechanism data expected 4Q2024.","Obesity: WVE-007 FIH study expected Q1 2025; preclinical data at R&D Day Fall 2024."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-24-196489","json":"https://secwatch.observer/filing/0001193125-24-196489.json","markdown":"https://secwatch.observer/filing/0001193125-24-196489.md","text":"https://secwatch.observer/filing/0001193125-24-196489.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1631574/000119312524196489/0001193125-24-196489-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1631574/000119312524196489/d875535d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-31T10:58:13.848546+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}