secwatch.observer — SEC 8-K summary
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Issuer:     Lantheus Holdings, Inc. (LNTH)
CIK:        0001521036
Form:       8-K
Filed at:   2024-09-25T23:59:59+00:00
Accession:  0001193125-24-226113
Event type: other_material
Sentiment:  neutral
Materiality: 0.65
Item codes: 7.01
LLM model:  deepseek-v4-flash:cloud@v2

Lantheus to release SPLASH trial data in Oct 2024 after 75% OS events reached
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- Expects to release Phase 3 SPLASH data in October 2024 for 177Lu-PNT2002 in PSMA-expressing mCRPC.
- Release triggered by reaching 75% of protocol-specified target overall survival events.
- Trial randomized 412 patients 2:1; 84.6% of control arm crossed over to PNT2002.
- Primary endpoint is radiographic progression-free survival; 80% of patients from North America.

Source:
  EDGAR index:    https://www.sec.gov/Archives/edgar/data/1521036/000119312524226113/0001193125-24-226113-index.htm
  Primary doc:    https://www.sec.gov/Archives/edgar/data/1521036/000119312524226113/d868473d8k.htm
  HTML page:      https://secwatch.observer/filing/0001193125-24-226113

License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer