{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-24-255157","form_type":"8-K","ticker":"WVE","cik":"0001631574","company_name":"Wave Life Sciences Ltd.","filed_at":"2024-11-12T23:59:59+00:00","discovered_at":"2026-05-14T18:03:09.042563+00:00","generated_at":"2026-05-30T01:58:07.940089+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Wave Life Sciences Q3 net loss $61.8M; first RNA editing in humans for AATD achieved","bullets":["Net loss $61.8M vs net income $7.3M in Q3 2023; revenue ($7.7M) vs $49.2M (including one-time events).","Cash $310.9M at Sep 30, 2024; plus ~$28M net proceeds from greenshoe; runway into 2027.","First-ever RNA editing in humans: WVE-006 in RestorAATion-2 showed mean M-AAT 6.9 µM at day 15 (60%+ of total AAT).","WVE-007 (INHBE GalNAc-siRNA) obesity clinical trial on track for 1Q 2025; preclinical data supports monotherapy and GLP-1 synergy.","WVE-003 HD: FDA open to caudate atrophy endpoint for accelerated approval; IND submission expected 2H 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-24-255157","json":"https://secwatch.observer/filing/0001193125-24-255157.json","markdown":"https://secwatch.observer/filing/0001193125-24-255157.md","text":"https://secwatch.observer/filing/0001193125-24-255157.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1631574/000119312524255157/0001193125-24-255157-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1631574/000119312524255157/d853532d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-30T01:58:07.940089+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}