other material
confidence high
sentiment positive
materiality 0.65
IN8bio Phase 1 INB-200 data: 50% of multi-dose patients alive beyond expected median OS
IN8BIO, INC.
- 50% of multi-dose patients (n=10) alive beyond expected median OS from Stupp regimen; none in single-dose group (n=3).
- Biopsy confirmed gamma-delta T cell persistence in brain tumor microenvironment in two patients post-treatment.
- Median PFS in repeat-dose patients increased 79% vs. 6.9 months for Stupp regimen.
- No treatment-related serious adverse events, cytokine release syndrome, or neurotoxicity reported.
- One IDH-mutant glioma patient remains alive and progression-free at 40.5 months.