---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-001834"
form_type: "8-K"
ticker: "SEPN"
cik: "0001984086"
company_name: "Septerna, Inc."
filed_at: "2025-01-06T23:59:59+00:00"
generated_at: "2026-05-28T11:35:58.752230+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# Septerna appoints Gil Labrucherie as CFO effective Jan 6, 2025; interim CFO Ran Xiao resigns

## Summary
- Gil Labrucherie appointed CFO, principal financial and accounting officer, effective Jan 6, 2025.
- Labrucherie brings 25+ years biotech experience, most recently CFO of Acelyrin and Nektar Therapeutics.
- Compensation includes $485k base salary, 40% target bonus, and stock option for 222,000 shares.
- Interim CFO Ran Xiao resigns from CFO role but remains VP of Finance and Business Operations.
- Labrucherie has raised over $1.5B in equity and generated $1B+ in strategic partnering value.

## SEC filing metadata
- accession: 0001193125-25-001834
- form_type: 8-K
- ticker: SEPN
- cik: 0001984086
- company_name: Septerna, Inc.
- filed_at: 2025-01-06T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1984086/000119312525001834/0001193125-25-001834-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1984086/000119312525001834/d753888d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-001834
- JSON: https://secwatch.observer/filing/0001193125-25-001834.json
- Plain text: https://secwatch.observer/filing/0001193125-25-001834.txt

## Key facts
- Executive change
  Gil M. Labrucherie was appointed as Chief Financial Officer at Septerna, Inc..
  - Action: appointed
  - Role: Chief Financial Officer
  source text: On December 23, 2024, the Board of Directors (the “Board”) of Septerna, Inc. (the “Company”) appointed Gil M. Labrucherie as the Chief Financial Officer, principal financial officer and principal accounting officer of the Company, in each case, effective as of January 6, 2025.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1984086/000119312525001834/0001193125-25-001834-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.