other material
confidence high
sentiment negative
materiality 0.90
Pliant Therapeutics pauses BEACON-IPF Phase 2b trial of bexotegrast after DSMB review
PLIANT THERAPEUTICS, INC.
- Voluntarily paused enrollment and dosing in BEACON-IPF Phase 2b trial of bexotegrast for idiopathic pulmonary fibrosis (IPF).
- Pause follows prespecified data review and recommendations by independent Data Safety Monitoring Board (DSMB).
- Patients currently enrolled in the trial will remain and be monitored while data is reviewed; blinding maintained.
- Company has informed trial investigators and is in process of informing global regulatory authorities.
- No details provided on DSMB rationale; lead asset trial halt likely materially negative for PLRX stock.