other material
confidence high
sentiment negative
materiality 0.75
Pliant assembles outside expert panel to review bexotegrast trial after DSMB pause recommendation
PLIANT THERAPEUTICS, INC.
- DSMB recommended pause of enrollment and dosing in BEACON-IPF Phase 2b trial of bexotegrast in IPF.
- Company initiated assembly of outside expert panel (pulmonary experts and biostatisticians) to review unblinded data.
- Company could not determine DSMB rationale from blinded data; panel will provide independent recommendation then join expanded DSMB.
- Process expected to conclude in 2-4 weeks; company remains blinded to maintain trial's potential as registrational.