---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-045671"
form_type: "8-K"
ticker: null
cik: "0001597553"
company_name: "Sage Therapeutics, Inc."
filed_at: "2025-03-04T23:59:59+00:00"
generated_at: "2026-05-25T14:02:21.835003+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.6
calibrated_materiality_score: 0.6
confidence: "high"
source: SEC EDGAR
---

# Sage Therapeutics CMO Laura Gault resigns, effective March 21; CSO Quirk to lead clinical programs on interim basis

## Summary
- Laura Gault, M.D., Ph.D. resigns as CMO effective March 21, 2025, to pursue a new opportunity.
- Resignation is not due to any disagreement with Sage Therapeutics.
- Mike Quirk, Ph.D., current CSO, will assume interim oversight of clinical development programs.

## SEC filing metadata
- accession: 0001193125-25-045671
- form_type: 8-K
- cik: 0001597553
- company_name: Sage Therapeutics, Inc.
- filed_at: 2025-03-04T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.6
- calibrated_materiality_score: 0.6
- confidence: high
- sec_items: 5.02, 8.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1597553/000119312525045671/0001193125-25-045671-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1597553/000119312525045671/d939383d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-045671
- JSON: https://secwatch.observer/filing/0001193125-25-045671.json
- Plain text: https://secwatch.observer/filing/0001193125-25-045671.txt

## Key facts
- Executive change
  Laura Gault resigned as Chief Medical Officer at Sage Therapeutics, Inc..
  - Action: resigned
  - Role: Chief Medical Officer
  source text: On March 3, 2025, Laura Gault, M.D., Ph.D. notified Sage Therapeutics, Inc. (the “Company”) of her decision to resign as Chief Medical Officer of the Company, effective March 21, 2025, to pursue a new opportunity.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1597553/000119312525045671/0001193125-25-045671-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.