8-K
filed March 20, 2025, 7:59 PM ET
ticker BNTC
CIK 0001808898
other material
confidence high
sentiment positive
materiality 0.75
Benitec reports durable improvements in swallowing function with BB-301 in OPMD interim results
Benitec Biopharma Inc.
- Three subjects treated with low-dose BB-301 showed significant, clinically meaningful improvements in swallowing function at 12 months (Subjects 1,2) and 3 months (Subject 3) post-treatment.
- Subject 1: 41% reduction in SSQ total symptom burden at 12 months; VFSS showed reductions in pharyngeal residue across all food and liquid consistencies.
- Subjects 2 and 3: near-complete resolution of pathologic sequential swallows; Subject 2 achieved clinically normal SSQ (68 units) at 12 months, Subject 3 at 3 months (70 units).
- No severe adverse events reported; five subjects safely treated; sixth and final Cohort 1 subject expected to receive low-dose BB-301 in Q2 2025.
Machine-readable event card
- schema_version
- secwatch.filing_event.v1
- accession
- 0001193125-25-059398
- form_type
- 8-K
- ticker
- BNTC
- cik
- 0001808898
- company_name
- Benitec Biopharma Inc.
- filed_at
- 2025-03-20T23:59:59+00:00
- discovered_at
- 2026-05-14T18:03:04.966406+00:00
- generated_at
- 2026-05-24T10:34:52.543478+00:00
- sec_items
- ["8.01"]
- event_type
- other_material
- sentiment
- positive
- materiality_score
- 0.75
- calibrated_materiality_score
- 0.75
- confidence
- high
- secwatch_canonical_url
- https://secwatch.observer/filing/0001193125-25-059398
- json_url
- https://secwatch.observer/filing/0001193125-25-059398.json
- markdown_url
- https://secwatch.observer/filing/0001193125-25-059398.md
- text_url
- https://secwatch.observer/filing/0001193125-25-059398.txt
- edgar_index_url
- https://www.sec.gov/Archives/edgar/data/1808898/000119312525059398/0001193125-25-059398-index.htm
- edgar_primary_document_url
- https://www.sec.gov/Archives/edgar/data/1808898/000119312525059398/d906340d8k.htm
- generated_by_model
- deepseek-v4-flash:cloud@v2
- review_status
- machine_generated
- human_reviewed
- false
- corrected
- false
- correction_note
- null
- correction_timestamp
- null
- superseded_by
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