---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-068880"
form_type: "8-K"
ticker: null
cik: "0001808158"
company_name: "Repare Therapeutics Inc."
filed_at: "2025-03-31T23:59:59+00:00"
generated_at: "2026-05-24T02:09:25.635431+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Repare Therapeutics CEO Segal resigns; CFO Steve Forte becomes CEO effective April 11

## Summary
- Lloyd Segal resigns as President, CEO, and Director effective April 11, 2025; not due to disagreement.
- Steve Forte (current EVP/CFO) appointed President, CEO, and Director effective same date; will remain CFO.
- Sandra Alves promoted to SVP, Chief Accounting Officer; salary raised to CA$350,000; granted 24,500 options and 4,100 RSUs.
- Company expects to complete MYTHIC trial enrollment Q2 2025; topline data for POLAR (Q3) and LIONS (Q4) trials.
- Company exploring strategic alternatives and partnerships across portfolio, including for lunresertib and camonsertib.

## SEC filing metadata
- accession: 0001193125-25-068880
- form_type: 8-K
- cik: 0001808158
- company_name: Repare Therapeutics Inc.
- filed_at: 2025-03-31T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1808158/000119312525068880/0001193125-25-068880-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1808158/000119312525068880/d923441d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-068880
- JSON: https://secwatch.observer/filing/0001193125-25-068880.json
- Plain text: https://secwatch.observer/filing/0001193125-25-068880.txt

## Key facts
- Executive change
  Steve Forte was appointed as President and Chief Executive Officer at Repare Therapeutics Inc..
  - Action: appointed
  - Role: President and Chief Executive Officer
  source text: the Board appointed Steve Forte to serve as the Company’s President and Chief Executive Officer in addition to his current role as the Company’s Chief Financial Officer, effective as of the Effective Date.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1808158/000119312525068880/0001193125-25-068880-index.htm
- Executive change
  Lloyd Segal resigned as President and Chief Executive Officer at Repare Therapeutics Inc..
  - Action: resigned
  - Role: President and Chief Executive Officer
  source text: On March 31, 2025, Lloyd Segal, President and Chief Executive Officer of Repare Therapeutics Inc. (the “ Company ”), notified the board of directors (the “ Board ”) of the Company of his resignation from his positions as President and Chief Executive Officer and as a member of the Board, effective April 11, 2025
  evidence_url: https://www.sec.gov/Archives/edgar/data/1808158/000119312525068880/0001193125-25-068880-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.