{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-25-157390","form_type":"8-K","ticker":"COGT","cik":"0001622229","company_name":"Cogent Biosciences, Inc.","filed_at":"2025-07-10T23:59:59+00:00","discovered_at":"2026-05-14T18:02:44.505172+00:00","generated_at":"2026-05-18T08:46:12.786566+00:00","sec_items":["1.01","2.02","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.9,"calibrated_materiality_score":0.9,"confidence":"high","headline":"Bezuclastinib SUMMIT trial beats all primary/secondary endpoints; NDA submission by end 2025","bullets":["SUMMIT trial met primary endpoint: mean TSS reduction of 24.3 vs 15.4 placebo (p=0.0002); 8.91-point placebo-adjusted improvement.","87.4% of bezuclastinib patients had ≥50% reduction in serum tryptase vs 0% placebo (p<0.0001).","NDA submission to FDA expected by end of 2025; plan to present full data at medical meeting.","Raised ~$230M gross via offering of 22.2M shares at $9 (plus underwriter option fully exercised).","Cash balance ~$237M as of June 30, 2025; access to up to $350M via debt facility."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-25-157390","json":"https://secwatch.observer/filing/0001193125-25-157390.json","markdown":"https://secwatch.observer/filing/0001193125-25-157390.md","text":"https://secwatch.observer/filing/0001193125-25-157390.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1622229/000119312525157390/0001193125-25-157390-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1622229/000119312525157390/d92808d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-18T08:46:12.786566+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}