other material
confidence high
sentiment positive
materiality 0.60
NCCN SCLC guidelines add LEMS testing and amifampridine (FIRDAPSE) treatment recommendation
CATALYST PHARMACEUTICALS, INC.
- NCCN guidelines for SCLC updated to recommend VGCC antibody testing for LEMS diagnosis.
- Amifampridine (FIRDAPSE) added as a supportive care treatment option for LEMS in SCLC.
- Approximately 50% of LEMS cases are cancer-associated, most commonly with SCLC.
- Catalyst internal analysis suggests 90% of LEMS in SCLC patients may be undiagnosed.
- Guideline inclusion could increase clinical awareness and drive adoption of VGCC testing and amifampridine use.