---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-184619"
form_type: "8-K"
ticker: "SCLX"
cik: "0001820190"
company_name: "Scilex Holding Co"
filed_at: "2025-08-21T23:59:59+00:00"
generated_at: "2026-05-17T10:55:42.032373+00:00"
event_type: "leadership"
sentiment: "positive"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Scilex CEO Jaisim Shah resigns to focus on Semnur; Henry Ji appointed CEO; Semnur gets $20M PIPE

## Summary
- Jaisim Shah resigned as CEO/President of Scilex effective Aug 17, 2025; remains on Board and will focus full time on Semnur.
- Henry Ji, previously Executive Chairman, appointed as Scilex's new CEO and President effective immediately.
- Semnur (majority-owned subsidiary) entered a $20M private placement at $16/share; proceeds fund SP-102 Phase 3 trial.
- The PIPE is contingent on Semnur's business combination with Denali Capital Acquisition Corp.
- Jaisim Shah's departure is to dedicate full attention to advancing SP-102 for LRP/Sciatica toward regulatory approval.

## SEC filing metadata
- accession: 0001193125-25-184619
- form_type: 8-K
- ticker: SCLX
- cik: 0001820190
- company_name: Scilex Holding Co
- filed_at: 2025-08-21T23:59:59+00:00
- event_type: leadership
- sentiment: positive
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1820190/000119312525184619/0001193125-25-184619-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1820190/000119312525184619/d27011d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-184619
- JSON: https://secwatch.observer/filing/0001193125-25-184619.json
- Plain text: https://secwatch.observer/filing/0001193125-25-184619.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.