{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-25-197610","form_type":"8-K","ticker":"RAPP","cik":"0002012593","company_name":"Rapport Therapeutics, Inc.","filed_at":"2025-09-08T23:59:59+00:00","discovered_at":"2026-05-14T18:02:45.813313+00:00","generated_at":"2026-05-17T07:44:51.463083+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"Rapport RAP-219 Phase 2a positive: 85.2% achieved ≥30% LE reduction, 24% seizure freedom","bullets":["85.2% of patients achieved ≥30% reduction in long episodes (p<0.0001); median LE reduction 71%.","72% achieved ≥50% reduction in clinical seizures (p<0.0001); 24% seizure freedom; median reduction 77.8%.","RAP-219 well tolerated: no SAEs; 78.5% of TEAEs mild; 10% discontinuation due to TEAEs.","Company plans end-of-Phase 2 FDA meeting Q4 2025; Phase 3 pivotal trials expected Q3 2026.","Additional programs: Phase 2 bipolar mania trial enrolling, topline H1 2027; diabetic neuropathic pain update later 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-25-197610","json":"https://secwatch.observer/filing/0001193125-25-197610.json","markdown":"https://secwatch.observer/filing/0001193125-25-197610.md","text":"https://secwatch.observer/filing/0001193125-25-197610.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/2012593/000119312525197610/0001193125-25-197610-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/2012593/000119312525197610/d919002d8k.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-17T07:44:51.463083+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}