Achieve Life Sciences CMO/President Dr. Cindy Jacobs resigns; stays as consultant through NDA approval

ACHIEVE LIFE SCIENCES, INC.

Dr. Jacobs resigned as Chief Medical Officer and President effective Oct 6, 2025.
Separation agreement includes lump-sum cash severance of $101,296 (prorated 2025 bonus).
She will serve as consultant until first business day after FDA NDA approval for cytisinicline.
Unvested time-based options from Jan 2023/Jan 2024 to accelerate upon consultancy end; exercise period extended to 12 months.
Company will reimburse up to $10,000 in legal fees for negotiation of separation and consulting agreements.

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