---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-268103"
form_type: "8-K"
ticker: "LNTH"
cik: "0001521036"
company_name: "Lantheus Holdings, Inc."
filed_at: "2025-11-06T23:59:59+00:00"
generated_at: "2026-05-16T23:38:51.503573+00:00"
event_type: "earnings"
sentiment: "neutral"
materiality_score: 0.85
calibrated_materiality_score: 0.85
confidence: "high"
source: SEC EDGAR
---

# Lantheus Q3 revenue $384M (+1.4% YoY), adj. EPS $1.27; CEO Markison to retire, Heino interim CEO

## Summary
- GAAP net income $27.8M ($0.41 fully diluted EPS); adjusted EPS $1.27, down 25.3% YoY.
- PYLARIFY sales $240.6M (-7.4% YoY); DEFINITY $81.8M (+6.3%). Free cash flow $94.7M.
- CEO Brian Markison retires Dec 31, 2025; President Paul Blanchfield leaves Nov 7.
- Mary Anne Heino appointed Executive Chair Nov 7, to serve as Interim CEO from Jan 1, 2026.
- FY2025 guidance: revenue $1.49B–$1.51B; adj. EPS $5.50–$5.65; $100M share repurchase in Q3.

## SEC filing metadata
- accession: 0001193125-25-268103
- form_type: 8-K
- ticker: LNTH
- cik: 0001521036
- company_name: Lantheus Holdings, Inc.
- filed_at: 2025-11-06T23:59:59+00:00
- event_type: earnings
- sentiment: neutral
- materiality_score: 0.85
- calibrated_materiality_score: 0.85
- confidence: high
- sec_items: 2.02, 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1521036/000119312525268103/0001193125-25-268103-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1521036/000119312525268103/lnth-20251031.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-268103
- JSON: https://secwatch.observer/filing/0001193125-25-268103.json
- Plain text: https://secwatch.observer/filing/0001193125-25-268103.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.