{"schema_version":"secwatch.filing_event.v1","accession":"0001193125-25-269533","form_type":"8-K","ticker":"CTMX","cik":"0001501989","company_name":"CytomX Therapeutics, Inc.","filed_at":"2025-11-06T23:59:59+00:00","discovered_at":"2026-05-14T18:02:39.573453+00:00","generated_at":"2026-05-16T23:38:26.712915+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"CytomX Q3 2025 revenue $6.0M (down 82% YoY); cash $143.6M; pipeline on track for key milestones","bullets":["Total revenue $6.0M in Q3 2025 vs $33.4M in Q3 2024; cash, equivalents and investments $143.6M, runway to Q2 2027.","R&D expenses $15.3M (-$6.1M YoY); G&A $6.4M (-$1.5M YoY); total operating expense $21.7M.","CX-2051 Phase 1 enrollment ~100 patients by Q1 2026 data update; Phase 1b combo with bevacizumab starts Q1 2026.","CX-801 Phase 1 monotherapy biomarker data at SITC 2025; combo with KEYTRUDA dose escalation enrolling 2nd dose level.","Appointed Rachael Lester as SVP, Chief Business Officer in October 2025."],"urls":{"canonical":"https://secwatch.observer/filing/0001193125-25-269533","json":"https://secwatch.observer/filing/0001193125-25-269533.json","markdown":"https://secwatch.observer/filing/0001193125-25-269533.md","text":"https://secwatch.observer/filing/0001193125-25-269533.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1501989/000119312525269533/0001193125-25-269533-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1501989/000119312525269533/ctmx-20251106.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T23:38:26.712915+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}