---
schema_version: "secwatch.filing_event.v1"
accession: "0001193125-25-269716"
form_type: "8-K"
ticker: "CDXS"
cik: "0001200375"
company_name: "CODEXIS, INC."
filed_at: "2025-11-06T23:59:59+00:00"
generated_at: "2026-05-16T23:23:01.358066+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.8
calibrated_materiality_score: 0.8
confidence: "high"
source: SEC EDGAR
---

# Codexis appoints Alison Moore CEO, cuts 24% workforce, signs $37.8M Merck deal; Q3 net loss $19.6M

## Summary
- Alison Moore appointed President and CEO effective Nov 7, 2025; Stephen Dilly becomes Executive Chairman.
- Workforce reduced by 46 positions (~24%); expects $3.5M expense in Q4 2025, substantially completed by Jan 2026.
- Signed $37.8M Supply Assurance Agreement with Merck; cash anticipated by year-end 2025.
- Q3 2025 revenue $8.6M (down from $12.8M YoY); net loss $19.6M ($0.22/share).
- Cash and investments $58.7M as of Sept 30, 2025; cash runway extended through 2027.

## SEC filing metadata
- accession: 0001193125-25-269716
- form_type: 8-K
- ticker: CDXS
- cik: 0001200375
- company_name: CODEXIS, INC.
- filed_at: 2025-11-06T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.8
- calibrated_materiality_score: 0.8
- confidence: high
- sec_items: 2.02, 2.05, 5.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1200375/000119312525269716/0001193125-25-269716-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1200375/000119312525269716/d80118d8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001193125-25-269716
- JSON: https://secwatch.observer/filing/0001193125-25-269716.json
- Plain text: https://secwatch.observer/filing/0001193125-25-269716.txt

## Source-grounded claims
- claim_id: 8f3e6bcdcfcc2ec91e249b20e870e7b1d1f7b260
  claim: CODEXIS, INC. announced a restructuring with charges of approximately $3.5 million affecting ECO Synthesis platform (approximately 24%).
  evidence_excerpt: benefits to impacted employees, as well as the payment of other expenses such as related tax costs, will result in the recognition of an additional expense of approximately $3.5 million. The Company anticipates this expense will be recognized in the fourth quarter of 2025 and paid primarily during the same period. The Company expects the workforce reduction to
  evidence_url: https://www.sec.gov/Archives/edgar/data/1200375/000119312525269716/0001193125-25-269716-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.